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Updated: Jul 9, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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免疫蛋白酶的功能维持了KMT2A复合体驱动的白血病中的致癌基因表达.

Nuria Tubío-Santamaría1,2, Ashok Kumar Jayavelu3,4, Tina M Schnoeder1,2

  • 1Innere Medizin C, Universitätsmedizin Greifswald, 17475, Greifswald, Germany.

Molecular cancer
|December 4, 2023
PubMed
概括

针对免疫蛋白酶体,特别是PSMB8,对KMT2A重组的急性髓性白血病 (AML) 显示出希望. 将免疫蛋白酶体抑制剂与梅因抑制剂结合起来,为AML治疗提供了一个新的治疗策略.

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