为COVID-19和流感住院后的急性后续症状的比较
Ting-Hui Liu1, Po-Yu Huang2, Jheng-Yan Wu3
1Department of Psychiatry, Chi Mei Medical Center, Tainan, Taiwan.
BMC medicine
|December 4, 2023
概括
与流感幸存者相比,住院COVID-19患者面临的后COVID状况和长期健康问题的风险更大. 这包括更高的异常呼吸率,疲劳和认知症状.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 有限的比较数据存在于COVID-19和流感之间的后急性后果,特别是后Omicron的出现.
- 之前的研究往往在显著的病毒进化和疫苗接种运动之前进行.
研究的目的:
- 调查COVID后疾病的流行情况.
- 为了比较COVID-19患者和流感患者的急诊室访问,住院和死亡的长期风险.
主要方法:
- 使用 TriNetX 全球健康研究网络进行的一项回顾性队列研究.
- 包括2022年1月1日至2023年1月1日期间被诊断患有COVID-19或流感的住院患者.
- 倾向性得分匹配,以确保COVID-19和流感组之间的基线特征平衡,随后是90-180天的随访期.
主要成果:
- 在COVID-19组中,任何后COVID-19疾病的发病率都较高 (17.9%对13.0%,HR 1.398).
- 在COVID-19幸存者中观察到异常呼吸,腹部症状,疲劳和认知症状的风险显著增加.
- COVID-19患者的复合结果风险更大,包括急诊室访问,住院和死亡 (27.5%与21.7%,HR 1.303).
结论:
- 与流感幸存者相比,住院COVID-19患者面临的长期并发症风险要高得多.
- 调查结果强调了COVID后条件的持续负担以及持续监测和研究的必要性.
- 这项研究强调了COVID-19在急性感染之外的明显的长期健康影响.
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