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Updated: Jul 9, 2025

Sedimentation Equilibrium of a Small Oligomer-forming Membrane Protein: Effect of Histidine Protonation on Pentameric Stability
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在临床实验室使用平衡透析估计自由药物度的测量不确定性

Raúl Rigo-Bonnin1, Virgínia Mas-Bosch1, Francesca Canalias2

  • 1Laboratori Clínic, IDIBELL, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.

Clinical chemistry and laboratory medicine
|December 5, 2023
PubMed
概括

本研究提出了一种方法,用于估计使用平衡透析 (ED) 的自由药物度测量中的测量不确定性 (MU). 准确的MU估计对于可靠的治疗药物监测 (TDM) 至关重要.

关键词:
平衡透析 透析是平衡透析的方法之一.测量不确定性 测量不确定性总的药物度是药物的总度.超高性能液态色谱与双重质谱相结合 (UHPLC-MS/MS)超过是一种超过.没有绑定/自由的药物度.

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