卷积计算机断层扫描在肺癌查中的成本效益:基于纳尔逊研究结果的队列模拟
Xuanqi Pan1,2, Evgeni Dvortsin1, David R Baldwin3,4
1Institute for Diagnostic Accuracy, Groningen, The Netherlands.
Journal of medical economics
|December 5, 2023
概括
每年使用低剂量CT的肺癌查 (LCS) 对英国高风险人口来说是具有成本效益的. 这一战略可以避免过早死亡,并改善质量调整寿命年 (QALYs),为健康和经济带来显著的好处.
科学领域:
- 卫生经济学 卫生经济学
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 肺癌仍然是全球癌症死亡的主要原因.
- 通过查进行早期检测可以显著改善患者的治疗结果和生存率.
- 英国国家卫生服务 (NHS) 为高风险人群寻求具有成本效益的干预措施.
研究的目的:
- 评估每年基于体积的低剂量计算机断层扫描 (CT) 用于肺癌查 (LCS) 的成本效益.
- 为了比较英国 (UK) 的无症状,高风险人口的LCS没有查.
- 为英国潜在的全国LCS实施提供证据.
主要方法:
- 从英国NHS的角度使用决策树和马尔科夫模型进行成本效益分析.
- 模拟肺癌识别,诊断和治疗途径.
- 在高风险队列中,每年CT查量与不进行查的比较.
主要成果:
- 年度LCS检测到96,474个早期肺癌,并在130万参与者中避免了53,732例过早死亡.
- 与没有查相比,观察到质量调整寿命年 (QALYs) 增加了421,647年.
- 增量成本效益比 (ICER) 为每QALY5455英,在敏感性分析中强.
结论:
- 年度LCS与基于体积的低剂量CT是一种高风险,无症状的英国人群的成本有效策略.
- 该干预措施代表了NHS资源的高效使用,改善了患者的治疗结果和社会利益.
- 调查结果支持基于证据的决定,在英国实施全国性的LCS计划.
关键词:
经济效益性 经济效益性D D D D D D D D D D D D D D D D D D D D D D D D D D D D D D D D D 在线观看 在线观看 在线观看D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D6 D7 D7 D7 D8 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9 D9D6060 D6060 D6060 D6060 D6060 D6060 D6060 DD61 D61 D61 D61 这是一个很好的例子.尼尔森 尼尔森是什么意思计算机断层扫描 (CT) 是一种计算机断层扫描.肺癌是一种肺癌.查检查 查检查 查检查 查检查更多相关视频
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