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运动训练在乳腺癌化疗期间有益于健康相关的生活质量和功能能力:一项随机对照试验
Pedro Antunes, Ana Joaquim, Francisco Sampaio
1Department of Mathematics and Center of Mathematics and Applications, University of Beira Interior, Covilhã, PORTUGAL.
监督运动训练 (SET) 有效地保持了与健康相关的生活质量 (HRQoL) 和接受早期乳腺癌 (BC) 化疗的女性的功能能力. 这种补充疗法有助于防止治疗期间病情恶化.
科学领域:
- 在瘤学瘤学.
- 运动科学 运动科学
- 生活质量研究 研究 生命质量研究
背景情况:
- 早期乳腺癌 (BC) 的化疗可能会对与健康相关的生活质量 (HRQoL) 和功能能力产生负面影响.
- 监督运动训练 (SET) 是一种潜在的干预措施,可以在治疗期间减轻这些不良影响.
研究的目的:
- 评估监督运动训练计划 (SETP) 对HRQoL和早期BC接受化疗的妇女的功能能力的有效性.
主要方法:
- 93名患有早期BC的女性被随机分配到SETP组 (n=47) 或常规护理 (UC) 组 (n=46).
- 该SETP包括3次每周的综合有氧和抵抗训练,同时进行化疗.
- 通过使用EORTC QLQ-C30和QLQ-BR23.3来评估HRQoL. 功能能力通过最大自愿握力 (MVHS) 和30秒椅子坐立测试 (30秒CST) 来测量.
主要成果:
- 与UC组相比,SETP组在全球健康状况,QLQ-C30总结得分,身体,角色,认知和社会功能方面的恶化较小.
- 运动组的疲劳和食欲丧失水平显著降低.
- 与UC相比,在SETP组的MVHS和30s CST分数中发现了改善.
结论:
- 监督运动训练是接受化疗的早期乳腺癌妇女的有效补充疗法.
- SET有助于防止常常与化疗治疗相关的HRQoL和功能能力下降.
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