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Updated: Jul 9, 2025

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额外的Lrp4高骨质突变通过增加骨重塑来缓解小鼠的Sost-Knockout表型

Gretl Hendrickx1,2, Eveline Boudin1, Ligia Mateiu1

  • 1Centre for Medical Genetics, University and University Hospital of Antwerp, Antwerp, Belgium.

Calcified tissue international
|December 5, 2023
PubMed
概括

硬质素 (SOST) 缺乏导致高骨质量,而LRP4变体可以影响骨重塑. 这项研究发现,LRP4变体部分减轻了SOST缺乏效应,在骨质和重塑方面观察到性别特异性差异.

关键词:
高骨质量 具有高骨质量一个Lrp4的.有关RNA测序的RNA测序骨质硬化症是一种硬化骨质.斯克莱洛斯在其中.这就是Sost Sost.

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