低收入和中等收入国家的利益相关者对核心成果集开发和使用的认识和经验:一项在线调查
Jamlick Karumbi1,2, Sarah Gorst1, David Gathara2,3
1Department of Health Data Science, University of Liverpool, Liverpool, United Kingdom.
PLOS global public health
|December 5, 2023
概括
利益相关者参与核心成果集 (COS) 对于低收入和中等收入国家 (LMICs) 的采用至关重要. 有限的参与和可行性问题阻碍了COS的使用,需要改善协作和可访问性.
科学领域:
- 临床试验 临床试验
- 健康研究方法 健康研究方法
- 全球健康 全球健康
背景情况:
- 通过核心结果集 (COS) 协调临床试验结果,减少了研究浪费,改善了翻译.
- 低收入和中等收入国家 (LMIC) 的利益相关者对 COS 开发和利用的参与有限.
- 了解LMIC利益相关者的观点对于有效实施COS至关重要.
研究的目的:
- 探索LMIC利益相关者的意识和经验,以了解COS的开发和使用.
- 确定在LMIC研究环境中采用COS的障碍和促进因素.
主要方法:
- 对LMIC利益相关者进行了一项在线调查.
- 受访者评估了三个病例情景COS (孕前,COVID-19,缓和护理) 的潜在用途.
- 定量数据被描述性地分析,定性数据被主题性地分析.
主要成果:
- 在81名受访者中,有26人有COS经验,9人参与开发.
- 由于感知到利益相关方的包容性,偏好使用先兆子和COVID-19 COS.
- 由于有限的参与和资源设置差异,息护理COS的使用是不确定的.
- 关键障碍包括结果的可行性,缺乏意识,利益相关方 (包括患者/护理人员) 的参与不足.
结论:
- 在LMICs中有效的COS开发和使用需要加强对意识,培训和发展的合作.
- COS必须以当地语言可访问,并且可以在LMIC环境中进行测量.
- 解决可行性和参与差距对于在LMICs中成功实施COS至关重要.
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