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相关概念视频

Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

4.1K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.1K
Regulation of Food Intake01:30

Regulation of Food Intake

244
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
244
Primary Motives: Hunger and Thirst01:25

Primary Motives: Hunger and Thirst

207
Hunger and thirst are fundamental physiological drives crucial for maintaining homeostasis and ensuring the survival of both humans and animals. These drives are regulated through complex interactions between the brain, hormones, and sensory receptors.
Hunger arises when the brain detects changes in the body's nutrient levels, including glucose, lipids, amino acids, and hormones such as ghrelin and leptin. The hypothalamus plays a central role in hunger regulation. The lateral hypothalamus...
207
Biological Clocks and Seasonal Responses02:45

Biological Clocks and Seasonal Responses

34.7K
The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
34.7K
Hormonal Regulation01:40

Hormonal Regulation

43.5K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
43.5K
Major Hormones and Their Functions01:27

Major Hormones and Their Functions

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Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
423

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Expression of clock genes tracks daily and tidal time in brains of intertidal crustaceans Eurydice pulchra and Parhyale hawaiensis.

Current biology : CB·2025
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Quantitative measures of clock protein dynamics in the mouse suprachiasmatic nucleus extends the circadian time-keeping model.

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相关实验视频

Updated: Jul 9, 2025

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
06:53

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Published on: November 11, 2016

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生物钟:对时间的渴望.

Michael H Hastings1

  • 1MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

Current biology : CB
|December 5, 2023
PubMed
概括

动物使用时间记忆来优化食. 一项新的研究揭示了这一至关重要的时间记忆嵌入了神秘的,光可引诱的昼夜钟.

科学领域:

  • 神经科学是一个神经科学.
  • 时间生物学 时间生物学
  • 动物行为 动物行为

背景情况:

  • 动物利用时间信息做出适应性食决策.
  • 了解时间感知和记忆的神经基础是生物学中的一个重大挑战.

研究的目的:

  • 为了研究从最后一顿饭以来的时间记忆背后的神经机制.
  • 为了确定昼夜时钟是否在时间记忆中起作用.

主要方法:

  • 使用动物模型进行行为实验.
  • 研究了昼夜时钟在时间记忆形成和回忆中的作用.

主要成果:

  • 证明动物可以记住自最后一次吃饭以来的时间.
  • 发现了令人信服的证据表明,这种时间记忆被编码在光可引诱的昼夜钟内.

结论:

  • 生物钟不仅参与日常节律,而且还参与编码特定的时间记忆,这对生存至关重要.
  • 这一发现为认知过程中昼夜系统的多方面的功能提供了新的见解.

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