独家母乳养促进干预对儿童结果的影响:系统性审查和元分析
Sarah Dib1, Frankie Joy Fair2, Lucy Jane McCann3
1UCL Great Ormond Street Institute of Child Health, London, UK.
促进纯母乳养 (EBF) 显著增加EBF率,并减少婴儿呼吸道疾病. 然而,这些干预措施并没有影响婴儿生长或死亡率,这表明婴儿早期健康有着有针对性的益处.
科学领域:
- 儿科 儿科 儿科
- 公共卫生 公共卫生
- 营养 营养 营养 营养 营养
背景情况:
- 纯母乳养 (EBF) 对婴儿健康至关重要,但关于干预有效性的证据是不一致的.
- 促进EBF的干预措施可能会带来健康益处,需要对现有数据进行全面审查.
研究的目的:
- 评估促进纯母乳养的干预措施对婴儿和7岁以下儿童健康结果的影响.
- 评估对生长,发病率和死亡率的影响,以及EBF率.
主要方法:
- 在多个数据库 (EMBASE,MEDLINE,CINAHL,Cochrane) 进行系统的文献搜索,直到2022年4月.
- 包括随机和集群随机对照试验,重点是增加EBF.
- 使用随机效应模型对增长,发病率和死亡率的聚合数据进行元分析.
主要成果:
- 分析了32项涉及40篇论文的研究.
- 促进EBF的干预措施显著改善了EBF率至6个月 (OR 3.15) 和减少了早期呼吸道疾病 (OR 0.41).
- 没有观察到对婴儿/儿童生长,住院或死亡率的显著影响;注意到对腹的边缘影响.
结论:
- 促进纯母乳养的干预措施有效地提高了EBF的发病率,并可能适度地降低婴儿发病率,特别是呼吸系统疾病.
- 这些干预措施似乎没有影响婴儿或儿童的成长.
- 建议对成本效益和更广泛的健康结果益处进行进一步的研究.
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