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Updated: Jul 9, 2025

Evaluating In Vitro DNA Damage Using Comet Assay
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Published on: October 11, 2017

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特莫索洛米德的特定运输不会取代DNA修复介导的化学抵抗

Katayun Bahrami1, Jussi Kärkkäinen1, Sania Bibi2

  • 1School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|December 5, 2023
PubMed
概括

改善药物输送并不是有效治疗脑瘤化疗的主要障碍. 研究人员发现,虽然一种新的前药物 (TMZ-AA) 更好地进入癌细胞,但它仍然需要DNA修复抑制剂来最大限度地抑制生长,这表明需要新的药物设计策略.

关键词:
化学抗药性 化学抗药性是一种抗药性.修复DNA的修复DNA的修复L型氨基酸输送器1 (LAT1) 是一种L型氨基酸输送器.一个药物产品.泰莫佐洛米德 (TMZ) 是一种

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