维生素D缺乏和非传染性脑膜炎:系统性审查和元分析
William Rojas-Carabali1, Juan Sebastián Pineda-Sierra2, Carlos Cifuentes-González2
1Neuroscience Research Group (NEUROS), Neurovitae Center for Neuroscience, Institute of Translational Medicine (IMT), Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia; Department of Bioinformatics, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore; Department of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
Autoimmunity reviews
|December 5, 2023
概括
维生素D缺乏与非传染性脑膜炎 (NIU) 的风险更高有关. 解决维生素D水平可能是管理这种炎症性眼病的潜在策略.
科学领域:
- 眼科医生 眼科 眼科
- 免疫学 免疫学 免疫学
- 营养科学 营养科学
背景情况:
- 维生素D对免疫功能至关重要,其缺乏与自身免疫性疾病有关.
- 维生素D缺乏和非传染性脑膜炎 (NIU) 之间的联系需要进一步调查.
研究的目的:
- 系统地审查和元分析维生素D缺乏和NIU之间的关系.
- 评估维生素D在NIU病变发生中的潜在作用.
主要方法:
- 在2023年5月8日之前,对三个数据库进行了系统搜索.
- 包括的观察性研究比较了NIU患者和健康对照者的维生素D水平.
- 随机效应的元分析是按照PRISMA和MOOSE指南进行的.
主要成果:
- 包括11项涉及354例NIU病例和5728例对照的研究.
- 维生素D缺乏与发展NIU的几率比率 (2.04) 显著增加有关.
- 大多数纳入的研究显示偏差风险较低.
结论:
- 维生素D缺乏是NIU的潜在危险因素.
- 需要进一步的前性研究来证实这些发现并探索机制.
- 查和解决维生素D缺乏症可能对NIU患者有益.
相关概念视频
Connective Tissue Cell Types
3.2K
Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
3.2K
Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K


