照明未经研究的GPCR-ome

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Sreeparna Majumdar1, Yi-Ting Chiu1, Julie E Pickett1

  • 1Department of Pharmacology, UNC Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA.

Drug discovery today
|December 5, 2023
PubMed
概括

"照亮可使用药物的基因组"项目提供了研究不足的G蛋白结合受体 (GPCRs) 的工具. 这些资源正在揭示它们的功能和药物潜力.

关键词:
敲进的小鼠 敲进的小鼠基于细胞的测定.化-EM结构的结构.发现药物的发现.高吞吐量选的高吞吐量选照亮可使用药物的基因组 (IDG).分子/化学探针的探测器.纳米体是一个纳米体.孤儿 GPCRs 的使用情况

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