职业农场工作活动影响工人的室内家庭微生物群
Kathryn R Dalton1, Mikyeong Lee1, Ziyue Wang2
1Genomics and the Environment in Respiratory and Allergic Health Group, Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, NC, USA.
Environmental research
|December 5, 2023
概括
农场工作任务和农药使用显著改变了家庭尘埃微生物群. 室内微生物组的这些变化可能会将职业暴露与农民健康和家庭福祉联系起来.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 职业健康 职业健康 职业健康
背景情况:
- 农场工作涉及各种影响农民健康的暴露.
- 室内家庭微生物群可能受到职业暴露的影响.
- 特定农场暴露量与家庭微生物组成之间的关系尚不清楚.
研究的目的:
- 调查农场工作活动和农药使用与室内微生物群之间的关联.
- 为了分析468名男性农民家中的尘埃微生物群.
主要方法:
- 来自农民卧室的尘埃样本的全基因组猎枪测序.
- 通过问卷评估6项农场工作任务和19种目前使用的/7种被禁止的农药成分.
- 对暴露与微生物多样性和组成之间的关联进行分析.
主要成果:
- 所有6个农场任务都增加了微生物多样性和改变了组成,具有剂量反应效应.
- 特定的微生物,包括基于土壤的共生生物,更为丰富.
- 草甘和林丹的使用与增加的微生物多样性相关;多种农药改变了微生物组成.
结论:
- 农场活动和农药暴露对家庭尘埃微生物群产生独特的影响.
- 家庭微生物组的变化可能会调解职业暴露对农民和家庭的健康影响.
- 这些发现表明了未来卫生干预措施的潜在目标.
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