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Updated: Jul 9, 2025

Expression, Solubilization, and Purification of Eukaryotic Borate Transporters
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细胞吸收中的立体选择性通过SLC22有机阴离子载体1,2,和3进行细胞吸收

Lukas Gebauer1, Ole Jensen1, Muhammad Rafehi1

  • 1Institute of Clinical Pharmacology, University Medical Center Göttingen, Göttingen D-37075, Germany.

Journal of medicinal chemistry
|December 5, 2023
PubMed
概括

药物载体的立体选择性对药物动力学至关重要. 这项研究表明,有机阴离子转运体 (OCT) 呈现基质特异性的立体选择性转运,影响药物行为.

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Facilitated Diffusion01:16

Facilitated Diffusion

The plasma membrane, a critical structure in cellular biology, houses an array of transporters, or carrier proteins, interspersed within its lipid bilayer. These proteins play a crucial role in solute transport through facilitated diffusion, a form of passive diffusion that uses transporters to move the molecules across the membrane.
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