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吸烟者的悖论在跨导管大动脉置换:从2015年到2020年的全国住院患者样本分析

Renxi Li¹, Qianyun Luo², Marat Yanavitski³

¹The George Washington University School of Medicine and Health Sciences, Washington, DC, United States of America; Division of Cardiovascular and Thoracic Surgery, Department of Surgery, University of Minnesota Medical School, Minneapolis, MN, United States of America.

Cardiovascular revascularization medicine : including molecular interventions

|December 5, 2023

概括

在最近的跨导管大动脉置换 (TAVR) 时代,吸烟者经历了"吸烟者悖论",与非吸烟者相比,显示出更好的结果和更低的死亡率. 需要进一步的研究来理解这种现象.

科学领域:

心血管医学心血管医学
干预心脏病学干预心脏病学
公共卫生公共卫生

背景情况:

吸烟是众所周知的心血管风险因素之一,但
吸烟者的悖论
之前在高危患者中观察到过透管后大动脉置换 (TAVR) 的结果更好.
TAVR的使用已扩展到较低风险人群中,需要更新研究.

研究的目的:

调查吸烟对TAVR结果在当前更广泛的患者群体的影响.

主要方法:

对2015-2020年国家住院样本 (NIS) 数据库的分析.
将TAVR患者分为吸烟者和非吸烟者的分层.
对住院结果的多变量分析,以程序前变量进行调整.

主要成果:

与非吸烟者相比,吸烟者 (n=23,683) 的住院死亡率,MACE,MI,中风和其他各种并发症明显较低 (n=35,251).
吸烟者也经历了更短的住院时间 (LOS) 和更低的医院费用.
调整后的几率比率表明,在许多不良事件中,吸烟具有保护作用.

结论:

这是一个很棒的节目,这是一个很棒的节目.
吸烟者的悖论
在当代TAVR时代仍然存在,吸烟者表现出改善的结果和降低的死亡率.
驱动这种悖论的潜在机制需要进一步深入研究.

关键词:

香烟香烟是一种烟草.吸烟吸烟吸烟吸烟在TAVRR中,我们可以看到.通过导管更换大动脉门.

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