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相关概念视频

Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.6K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

2.8K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Major Hormones and Their Functions01:27

Major Hormones and Their Functions

423
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
423
The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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相关实验视频

Updated: Jul 9, 2025

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
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德黑兰甲状腺功能障碍的患病率增加 - HAMRAH研究

Zahra Ghaemmaghami1, Parisa Firoozbakhsh2, Delara Gholami3

  • 1Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Vali-Asr Ave, Tehran, 1995614331, Iran.

BMC endocrine disorders
|December 5, 2023
PubMed
概括

这项研究评估了德黑兰的甲状腺功能障碍,发现10.3%的患病率,甲状腺功能障碍更常见,特别是在女性中. 这些发现凸显了城市伊朗人群中甲状腺健康意识的需要.

关键词:
群组研究是指群组研究.甲状腺功能过强症 甲状腺功能过强症甲状腺功能低下症 甲状腺功能低下症伊朗 伊朗 伊朗 伊朗流行程度 流行程度甲状腺疾病 甲状腺疾病

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科学领域:

  • 内分泌学 在内分泌学.
  • 公共卫生 公共卫生
  • 流行病学 流行病学

背景情况:

  • 甲状腺功能障碍在城市人口中是一个重大的健康问题.
  • 了解其流行率和风险因素对于有针对性的干预至关重要.
  • 德黑兰的城市人口是研究现代健康趋势的关键人口统计数据.

研究的目的:

  • 为了确定德黑兰城市人口中各种类别的甲状腺功能障碍的患病率.
  • 为了确定甲状腺功能障碍的相关风险因素.
  • 提供伊朗甲状腺健康的最新数据.

主要方法:

  • 这是一项HAMRAH前性队列的子研究,分析了2228名年龄在30-75岁之间的成年人的数据.
  • 血液样本测量了甲状腺刺激激素 (TSH),甲状腺素 (T4) 和三甲状腺素 (T3) 的水平.
  • 患病率包括被诊断为功能障碍的人和服用甲状腺药物的人.

主要成果:

  • 甲状腺功能障碍的总体患病率为10.3% (甲状腺功能低下:9.4%,甲状腺功能过高:0.9%).
  • 亚临床甲状腺功能低下症影响7%和亚临床甲状腺功能过强症1.6%的人口.
  • 甲状腺功能障碍在女性参与者中明显更常见 (P=0.029).

结论:

  • 该研究提供了有关德黑兰甲状腺功能障碍患病率的最新数据.
  • 临床和亚临床的甲状腺功能低下症在这个伊朗人群中比以前报告的更为普遍.
  • 女性性别成为甲状腺功能障碍的重要危险因素.