图像和性能增强药物对心房结构和功能的影响 抵抗训练的个体的心房结构和功能
Florence Place1, Harry Carpenter1, Barbara N Morrison2
1Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Tom Reilly Building, Byrom Street, Liverpool, L3 3AF, UK.
Echo research and practice
|December 5, 2023
概括
目前使用图像和性能增强药物 (IPEDs) 的用户显示心房应变和心房功能减少. 然而,在停止使用IPED后,这些心脏变化似乎是可逆的,这表明恢复的可能性.
科学领域:
- 心脏病学 心脏病学
- 运动医学 运动医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 图像和性能增强药物 (IPED) 在抵抗训练 (RT) 个人中很普遍.
- 已知IPEDs会对左心室 (LV) 的结构和功能产生负面影响.
- IPED对心房结构和功能的影响,特别是双心房应变的影响,仍未得到充分研究.
研究的目的:
- 调查当前与过去IPED使用对RT个体心房结构和功能的影响.
- 根据其IPED使用状态,评估RT个体的双心房菌株参数.
- 为了比较当前,过去和非IPED用户之间的心脏功能和结构.
主要方法:
- 采用横截面研究设计,对96名经过抵抗训练的个人 (81名男性,15名女性) 进行了研究.
- 根据调查问卷,参与者被分为IPED的当前 (n=57),过去 (n=19) 和非用户 (n=20).
- 通过应变成像的胸外回声心脏图像被用来评估心脏结构和功能,数据以全米尺度缩小到身体表面积 (BSA).
主要成果:
- 与过去和非用户相比,当前的IPED用户表现出更大的体重和BSA.
- 当前用户的绝对左和右心房体积/区域较大,但在全米缩放后正常化.
- 与过去和非使用者相比,当前的IPED使用者表现出明显的左下和右心房水库和导管应变,减少了LV透静功能,增加了左心房硬度.
结论:
- 当前IPED使用者的双心房扩大部分与身体尺寸的增加有关,通过全米缩放进行正常化.
- 当前IPED使用者的心房压力降低和LV扩张功能受损表明病理适应.
- 过去和非使用者之间的心脏参数相似性表明,与IPED使用相关的病理变化可能在戒断后可逆.
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