与低酸相比,赫西丁凝的消毒效果:通过元分析进行系统性审查
Theodoro Weissheimer1, Karem Paula Pinto2, Emmanuel João Nogueira Leal da Silva2,3
1Department of Endodontics, School of Dentistry, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Restorative dentistry & endodontics
|December 6, 2023
概括
赫西丁 (CHX) 凝和甲 (NaOCl) 在根管中表现出类似的消毒能力. 这次系统性审查没有发现这些药物之间的细菌或内毒素减少有显著差异,尽管需要更多的研究.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 微生物学 微生物学
- 传染性疾病 传染性疾病
背景情况:
- 低酸 (NaOCl) 是牙周内科的黄金标准灌剂.
- 赫西丁 (CHX) 凝是一种具有实质性的替代消毒剂.
- 对比它们的消毒剂有效性对于临床决策至关重要.
研究的目的:
- 系统地比较赫西丁 (CHX) 凝和二酸盐 (NaOCl) 的消毒能力.
- 评估这些灌剂对根管中的细菌和内毒素减少的影响.
主要方法:
- 在2022年12月之前,对多个数据库进行系统的文献搜索.
- 仅包括随机临床试验 (RCT).
- 细菌和内毒素减少的元分析,带有偏差风险和证据质量评估.
主要成果:
- 包括6个RCT,其中5个具有偏差风险低.
- 对细菌减少的元分析显示没有显著差异 (MD,75.03;P=0.67).
- 对内毒素减少的元分析也显示没有显著差异 (MD,20.59;P=0.48).
结论:
- 目前的证据表明,CHX凝和NaOCl之间的消毒能力没有显著差异.
- 需要进一步进行高质量的随机临床试验来证实这些发现.
- 这两种药物在化学机械制剂中的消毒中看起来都是可比的.
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