吸烟对塔科苏博综合征的影响:来自国际队列的见解
Iván J Núñez-Gil1,2, Francesco Santoro3, Ravi Vazirani1
1Cardiology Department, Hospital Clínico San Carlos, Madrid, Spain.
Frontiers in cardiovascular medicine
|December 6, 2023
概括
目前吸烟者患有塔科苏博综合征 (TTS) 呈现出明显的临床特征,并经历更长的住院时间. 然而,吸烟并没有独立影响TTS患者的长期死亡率.
科学领域:
- 心脏病学 心脏病学
- 临床医学 临床医学
- 公共卫生 公共卫生
背景情况:
- 塔科苏博综合征 (TTS) 是一种急性心脏病.
- 吸烟对TTS结果的影响需要进一步调查.
研究的目的:
- 评估烟草使用对被诊断患有塔科图苏博综合征的患者急性和长期结局的影响.
主要方法:
- 来自国际多中心德语意大利西班牙语Takotsubo注册表 (GEIST) 的患者分析.
- 在队列中,当前吸烟者与非吸烟者之间的比较.
- 使用 1:1 倾向分数匹配 (PSM) 进行调整分析.
主要成果:
- 目前吸烟者 (17%) 较年轻,女性较少,并较少患有高血压和糖尿病等并发症.
- 吸烟者患肺部和/或精神疾病的患病率更高.
- 吸烟者住院时间较长 (10天而不是9天),但住院并发症率相似.
- 长期随访显示,吸烟者与非吸烟者之间的年死亡率没有显著差异.
结论:
- 吸烟与TTS患者的特定人口和临床特征有关.
- 虽然吸烟与住院时间较长有关,但它似乎不是TTS死亡率的独立预测因素.
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