慢性病患者的感觉神经听力损失:综合性审查
Manasi Agrawal1, Chandra Veer Singh2
1Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus
|December 6, 2023
概括
慢性病 (CKD) 与更高的听力损失患病率有关,特别是感觉神经听力损失 (SNHL). 这种联系会影响患者的生活质量,可能源于共同的生理路径或耳毒药物.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 听力学 听力学是指听力学.
背景情况:
- 慢性病 (CKD) 与各种耳鼻喉科问题有关,包括听觉静脉系统损伤.
- 感觉神经听力损失 (SNHL) 是慢性病患者常见的并发症,影响他们的生活质量.
- 现有的研究表明,CKD和听觉功能障碍之间存在联系,尽管基于人口的研究有限.
研究的目的:
- 为了确定慢性病 (CKD) 患者听力损失的患病率.
- 调查慢性病患者感觉神经听力损失 (SNHL) 的潜在原因.
- 突出听力损失对CKD患者生活质量的影响.
主要方法:
- 关于CKD和听力损失的现有研究的文献综述.
- 分析拟议的病理生理机制,将功能与内耳健康联系起来.
- 检查耳毒药在CKD相关听力损失中的作用.
主要成果:
- 在CKD和增加听力损失风险之间存在显著的关联,包括SNHL.
- 潜在的机制包括脏和内耳之间的共同功能/结构相似性,电解质失衡和耳毒药物效应.
- 与健康人相比,CKD患者表现出前庭功能障碍的可能性更高.
结论:
- 听力损失是CKD患者普遍出现的并发症,对他们的生活质量产生负面影响.
- 了解CKD相关听力损失背后的机制对于早期检测和管理至关重要.
- 需要进一步的研究来充分阐明这种关系,并制定有针对性的干预措施.
相关概念视频
01:17Factors Affecting Renal Clearance: Renal Impairment
99
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
99
01:10Nephrons
2.5K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
2.5K
01:11Renal Failure: Dose Adjustments
95
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
95
01:20Renal Corpuscle
2.3K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
2.3K
01:27Dialysis
322
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
322