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[在评估恶性质瘤中MGMT基因促进者状态时的总DNA甲基化概况]

E I Petrova1, S A Galstyan1, E N Telysheva1

  • 1Burdenko Neurosurgical Center, Moscow, Russia.

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko
|December 6, 2023
PubMed
概括

甲基化O-6-methylguanine-DNA甲基转移酶 (MGMT) 基因促进体是质母细胞瘤的一个关键生物标志物. 分析总DNA甲基化概况可以准确地确定MGMT促进者状态,有助于治疗决策.

关键词:
通过DNA甲基化.艾卢米纳EPIC甲基化微阵列在MGMT基因促进者地位上.中枢神经系统瘤的表观遗传学恶性质质瘤是一种恶性质瘤.分子诊断 分子诊断 分子诊断

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