相关实验视频

Updated: Jul 9, 2025

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
07:04

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

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抗体与PD-1/PD-L1蛋白质的分子相互作用

Sofia Vasilakaki1, Ioannis Vathiotis2, Emmanouil Panagiotou2

  • 1Chemistry Department, National & Kapodistrian University of Athens, Panepistimiopolis, Athens, 15771, Greece.

Immunotherapy
|December 6, 2023
PubMed
概括

针对编程细胞死亡蛋白1 (PD-1) 和其配体 (PD-L1) 的抗体表现出明显的蛋白质-蛋白质相互作用. 结合亲和力的这些差异可能解释了这些免疫检查点抑制剂观察到的不同临床疗效.

关键词:
在PD-1中使用PD-1.在PD-L1中.它们是Atezolizumab.在此之前,Avelumab.达尔瓦卢马布 (Durvalumab) 是一种耐药的药物.这就是尼沃卢马布 (nivolumab).这就是Pembrolizumab.

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