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Updated: Jul 9, 2025

Molecular Modulation by Lentivirus-Delivered Specific shRNAs in Endoplasmic Reticulum Stressed Neurons
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Published on: April 24, 2021

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氨基酸剥夺通过NRF2下调来诱导TXNIP的表达

Se Hee Ahn1,2, Se-Kyeong Jang1, Yu Jin Kim1,2

  • 1Division of Fusion Radiology Research, Korea Institute of Radiological & Medical Sciences, Seoul, Republic of Korea.

IUBMB life
|December 6, 2023
PubMed
概括

氨基酸的限制,特别是阿尔金因,谷氨酸,氨酸和氨酸的限制,增加了肺癌细胞中硫素相互作用蛋白 (TXNIP) 的表达. 这种增加与氧化应激和NRF2下调有关,这表明了新的癌症治疗点.

关键词:
氨基酸剥夺 氨基酸剥夺非小细胞肺癌的肺癌.核因子红色素2相关因子2的核因子.有活性氧物种的反应性氧物种.甲素相互作用的蛋白质.

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