益生菌,益生菌和食物过敏:一个审查
1Department of Paediatric, Sousa Martins Hospital, Guarda's Health Local Unit, Guarda, Portugal.
European annals of allergy and clinical immunology
|December 6, 2023
概括
益生菌对治理牛奶和花生过敏有前途,有助于耐受性和脱敏. 然而,对于用益生菌预防食物过敏的有力证据仍然缺乏,需要进一步研究.
科学领域:
- 免疫学 免疫学 免疫学
- 胃肠病学 胃肠病学
- 过敏学 过敏学
背景情况:
- 食物过敏,包括牛奶蛋白过敏 (CMA) 和花生过敏,是严重的健康问题.
- 目前的研究探讨了益生菌和益生菌在管理和预防这些疾病中的作用.
- 现有证据表明,特定益生菌在获得耐受性和脱敏性方面具有潜在的益处.
研究的目的:
- 审查目前关于益生菌和益生菌在食品过敏的管理和预防中的使用证据.
- 评估益生菌在牛奶蛋白过敏 (CMA) 和花生口服免疫疗法 (OI) 中的疗效.
- 评估益生菌和益生菌在更广泛的预防食物过敏中的作用.
主要方法:
- 在PubMed/Medline上对2011年至2021年间发表的文章进行了全面的文献搜索.
- 搜索查询将"食物过敏"的术语与"益生菌"或"益生菌前生物"结合起来.
- 在分析了标题和摘要后,对54篇选定的文章进行了叙事审查.
主要成果:
- 对于CMA,与Lactobacillus Rhamnosus GG广泛化素配方可能有助于建立耐受性和缓解症状.
- 在花生口服免疫疗法 (OI) 中,Lactobacillus Rhamnosus CGMCC 1.3724 显示了持续脱敏的潜力.
- 益生菌预防食物过敏的证据并不强大,尽管母乳中的寡糖化合物有望预防亚托皮炎,食物过敏和喘.
结论:
- 益生菌显示出作为牛奶蛋白过敏 (CMA) 和花生口服免疫疗法 (OI) 的治疗辅助剂的潜力.
- 关于最佳益生菌菌株,剂量和治疗持续时间存在不一致.
- 进一步的研究对于阐明益生菌和益生菌在食物过敏管理和预防中的确切作用至关重要.
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