相关实验视频

Updated: Jul 9, 2025

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

甲状腺眼病中的分子生物标志物:文学综述

Hans Olav Ueland¹, Mikael Thomassen Neset¹, Paal Methlie^2,3

¹Department of Ophthalmology.

Ophthalmic plastic and reconstructive surgery

|December 6, 2023

概括

目前的甲状腺眼病 (TED) 生物标志物缺乏诊断准确性. 研究正在进行中,以找到更好的分子标记物,特别是眼生物标记物的面板,以改善对这种Graves病并发症的诊断和患者护理.

科学领域:

眼科医生眼科眼科
内分泌学在内分泌学.
免疫学免疫学免疫学

背景情况:

甲状腺眼病 (TED) 是一个常见的Graves病并发症,导致严重的症状,如视力丧失.
现有的生物标志物,如TSH受体自身抗体,缺乏最终的诊断准确性.
改进的诊断和预后生物标志物对于早期TED检测至关重要,特别是在亚临床或甲状腺功能障碍前阶段.

结论:

血清TSH受体自身抗体仍然是TED的唯一临床有用的分子生物标志物.
对新型生物标志物的进一步研究,特别是液中的多标志物面板,是必不可少的.
开发精确的生物标志物将大大提高TED的诊断能力和患者管理.

更多相关视频

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis

Published on: February 9, 2024

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model

Published on: October 6, 2023

相关概念视频

Synthesis and Regulation of Thyroid Hormones

Synthesis and Regulation of Thyroid Hormones

Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...