甲状腺功能障碍 视觉神经病变
Arnaud R G G Potvin1, Farzad Pakdel2, Peerooz Saeed1
1Orbital Center Amsterdam, Department of Ophthalmology, Amsterdam University Medical Center, location AMC, The Netherlands.
Ophthalmic plastic and reconstructive surgery
|December 6, 2023
概括
甲状腺视神经病变 (DON) 是甲状腺眼病 (TED) 的严重并发症,需要及时诊断和多学科管理. 虽然葡萄糖皮质类药物是第一线药物,但新的生物药物为这种危及视力的疾病提供了未来的治疗潜力.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 神经学 神经学
背景情况:
- 甲状腺视神经病变 (DON) 是甲状腺眼病 (TED) 的危险视力并发症,影响5-8%的患者.
- 眼神经压缩是主要的致病机制,年龄,男性性别,吸烟和糖尿病是危险因素.
结论:
- 尽管迅速治疗,但DON可能会导致永久的视力损伤.
- 静脉注射甲基普雷迪尼索隆仍然是主要的治疗方法,手术作为次要选择.
- 生物制剂是DON管理的有希望的未来途径,需要进一步研究.
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