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Updated: Jul 9, 2025

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography
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对FXR激动剂的合理设计:用于NASH治疗的计算方法

Akshata Gandhe1, Sonia Kumari1, Masilamani Elizabeth Sobhia2

  • 1Department of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, Mohali, Punjab, 166062, India.

Molecular diversity
|December 6, 2023
PubMed
概括

研究人员设计了一种新的非类固醇FXR激动剂DB15416,用于治疗非酒精性脂肪肝炎 (NASH). 这种有前途的化合物通过准胆酸过程的关键调节者FXR,显示出NASH治疗的潜力.

关键词:
停靠对接 停靠对接外汇汇率激进剂 (ForexR) 是一种对外汇汇率激进剂.在MMGBSASA中,您可以使用MMGBSA.分子动力学分子动力学纳什·纳什 (Nash Nash) 是一个名为纳什的城市.药科类动物 (Pharmacophore) 是一种药科类动物.托罗皮菲克索尔 (Tropifexor) 是一种可怕的药物.

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