在患有昏迷和导电障碍的查加斯患者中进行电生理学研究
Alexia Hallack Dreicon1, Luciana Armaganijan1, Dalmo Antonio Ribeiro Moreira1
1Dante Pazzanese Institute of Cardiology, Electrophysiology and Clinical Arrhythmias - São Paulo (SP), Brazil.
Revista da Associacao Medica Brasileira (1992)
|December 6, 2023
概括
在查加斯病患者的电生理学研究中,昏迷和导电障碍经常会诱导恶性心室节律失常. 风险因素包括QRS宽度,HV间隔延长,射出分数减少和拉西得分更高.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 传染性疾病 传染性疾病
背景情况:
- 昏迷评估通常使用电生理学研究 (EPS) 治疗心脏导电障碍.
- 关于EPS在查加斯病患者的有用性存在相互矛盾的证据.
研究的目的:
- 评估查加斯病患者有昏迷和导电异常的电生理学研究结果.
- 在这个人群中确定恶性心室节律失常的预测因子.
主要方法:
- 对45名查加斯病患者进行EPS进行昏迷的回顾性分析 (2017-2021).
- 排除患有非可解读心电图,冠状动脉疾病或其他心肌病的患者.
- 对HV间隔和EPS诱导的心室心律不整的分析.
主要成果:
- 超过一半 (57.8%) 的患者患有可诱导的恶性心室心律不整.
- 平均HV间隔为58.37毫秒,其中22.2%的间隔较长 (≥70毫秒).
- β阻塞剂,阿米奥达龙,NYHA类≥II,宽QRS,长时间的HV间隔,高拉西得分和减少的射出分数预测可诱导的失律.
结论:
- 诱导性恶性心室节律失常在夏加斯病患者中常见,这些患者有昏迷和导电障碍.
- 长时间的HV间隔比预期的少,但仍然是一个危险因素.
- 广泛的QRS,延长的HV,减少喷射分数和更高的拉西得分与心律失常风险增加有关.
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