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Updated: Jul 9, 2025

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弗拉盖林诱导的NAIP5激活的结构基础

Bhaskar Paidimuddala1, Jianhao Cao1, Liman Zhang1

  • 1Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, OR 97239, USA.

Science advances
|December 6, 2023
PubMed
概括

在NLR家族的亡抑制蛋白 (NAIP) 炎症酶使用"陷和锁"机制来结合细菌鞭毛蛋白 (FliC). 这种相互作用触发了对抗格兰氏阴性细菌的免疫防御必不可少的结构变化.

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