老年人营养风险指数独立预测了重症监护病房中老年患者的痴呆症:一个多中心队列研究
Fangxin Wei1, Hongtao Cheng1, Ruiyao He1
1School of Nursing, Jinan University, Guangzhou, Guangdong, China.
Archives of gerontology and geriatrics
|December 6, 2023
概括
营养不良会增加老年ICU患者的妄想风险. 老年营养风险指数 (GNRI) 可以预测痴呆症,改善风险评估和患者的结果.
科学领域:
- 老年医学 老年医学
- 密集护理医学 密集护理医学
- 营养科学 营养科学
背景情况:
- 营养不良与各种疾病的不良结果有关.
- 营养不良对老年ICU患者妄风险的具体影响尚未得到充分证实.
- 这项研究调查了老年营养风险指数 (GNRI) 以及它与该人口中妄想症的关联.
研究的目的:
- 确定老年营养风险指数 (GNRI) 是否与入住重症监护室 (ICU) 的老年患者痴呆风险增加有关.
- 评估GNRI对危重病老年人痴呆症发展的预测价值.
主要方法:
- 利用了来自密集护理IV (MIMIC-IV) 和eICU协作研究数据库 (eICU-CRD) 的医疗信息中心的数据,其中分别包括11,310名和5,627名老年患者.
- 根据GNRI得分分层的患者分为四组:没有风险,轻度风险,中度风险和严重风险.
- 评估了妄想作为主要结果,并使用多变量模型分析了与GNRI类别的关联.
主要成果:
- 老年人营养风险指数 (GNRI) 与所有营养风险类别 (轻度,中度,重度) 的狂妄症风险增加显著相关,与没有营养风险相比.
- 患有严重营养风险 (GNRI < 82) 的患者患上妄想的几率最高 (OR: 2.07).
- 将GNRI得分纳入多变量模型提高了 Delirium 的预测准确性.
结论:
- 根据老年营养风险指数 (GNRI) 评估的营养状况似乎是老年ICU患者痴呆症的独立预测因素.
- GNRI可以提高妄想预测模型的准确性,有助于早期识别和干预.
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