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Updated: Jul 9, 2025

Assay Development for High Content Quantification of Sod1 Mutant Protein Aggregate Formation in Living Cells
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与ALS相关的SOD1突变损害了线粒体衍生的囊泡形成,加速了衰老

Ying Guo1, Teng Guan2, Qiang Yu2

  • 1Department of Human Anatomy and Cell Science, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Canada; Department of Forensic Medicine, Hebei North University, Zhangjiakou, China.

Redox biology
|December 6, 2023
PubMed
概括

来自ALS相关突变的氧化超氧化脱酶1 (SOD1) 导致过早衰老和细胞衰老. 消除氧化SOD1减缓了衰老,证实了它在衰老过程中的因果作用.

关键词:
衰老的衰老 衰老的衰老细胞衰老 细胞衰老线粒体功能障碍 线粒体功能障碍由线粒体衍生的囊泡.氧化应激是一种氧化应激.超氧化物脱酶 1 超氧化物脱酶

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