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作为粉样β (Aβ) 聚合抑制剂的双功能脊柱改性方二

Suchita Dattatray Shinde1, Santosh Kumar Behera2, Neeraj Kulkarni1

  • 1Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER)-Ahmedabad, Gujarat 382355, India.

Bioorganic & medicinal chemistry
|December 6, 2023
PubMed
概括

新的双功能二对阿尔茨海默病 (AD) 治疗具有前景,通过同时抑制粉样β (Aβ) 聚合和减少金属离子应激,同时抑制粉样β (Aβ) 聚合. 这些化合物也表现出抗氧化特性,提供了潜在的治疗支架.

关键词:
阿尔茨海默病 (AD) 是一种疾病.抗氧化剂是一种抗氧化剂.这是一种Aβ聚合抑制剂.双功能脊柱改性二化物金属化剂是金属化剂.斯克瓦拉米德斯 (Squaramides) 是一个方形人.

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