在患有抗脂综合征的患者中进行全膝关节关节整形术后的风险
Zhichang Zhang1, Jialun Chi2, Ian Duensing2
1Department of Orthopaedic Surgery, University of Virginia School of Medicine, Charlottesville, Virginia; Department of Orthopaedic Surgery, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan, China.
The Journal of arthroplasty
|December 6, 2023
概括
患有抗脂综合征 (APS) 的患者在膝关节全关节整形术 (TKA) 后面临更高的中风和深静脉血栓的风险. 外科医生应考虑对接受TKA的APS患者进行增强型血栓形成预防.
科学领域:
- 整形外科手术 整形外科手术
- 类风湿病学 类风湿病学
- 血管医学 血管医学
背景情况:
- 抗脂综合征 (APS) 是一种自身免疫性疾病,增加了血栓形成的风险.
- 膝关节整形术 (TKA) 是膝关节关节炎的一种常见手术.
- 在APS患者中,与TKA相关的血栓形成风险尚未得到充分证实.
研究的目的:
- 调查抗脂综合征 (APS) 作为一次性膝关节全关节整形术 (TKA) 后并发症的危险因素.
主要方法:
- 使用PearlDiver Mariner数据库对从2010年到2022年接受初级TKA的7478名患者进行了回顾性分析.
- 683名APS患者与基于年龄,性别和并发症的10:1匹配对照组进行了比较.
- 多变量逻辑回归分析了医疗和手术并发症,分别为90天和2年.
主要成果:
- 在TKA后90天内,APS患者的脑血管事故 (中风) (aOR2.04) 和深静脉血栓 (DVT) (aOR2.87) 发生率显著增加.
- 在APS和对照组之间,在手术并发症或非血栓性医疗问题上没有发现显著差异.
- 九十天的急诊室访问和住院再入院在队列之间没有统计学上的差异.
结论:
- 抗脂综合征 (APS) 与膝关节关节整形术 (TKA) 后中风和深静脉血栓形成的风险增加有关.
- 其他手术并发症和再入院率在APS患者和对照人群之间是可比的.
- 在接受TKA的APS患者中,应仔细考虑外科手术期间的血栓形成预防.
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