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洋补充剂和健康代谢参数:随机对照试验的系统审查和元分析

Najmeh Hejazi¹, Hamid Ghalandari², Mehran Nouri²

¹Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.

Clinical nutrition ESPEN

|December 6, 2023

概括

洋补充剂对关键健康标志物产生积极影响,包括身体脂肪,胆固醇和血压. 较长时间和较高剂量的洋摄入量会在心脏代谢健康方面带来更大的改善.

科学领域:

营养科学营养科学
代谢健康代谢健康
饮食干预饮食干预

背景情况:

功能性食品,如洋,越来越多地研究其对健康的益处.
关于洋补充对代谢参数的影响现有的研究是分散的.
需要进行全面的分析来巩固关于洋影响的发现.

研究的目的:

系统地审查和分析洋补充对人体,脂质,血糖,肝脏和血压参数的影响.
调查干预时间和剂量对这些健康结果的影响.

主要方法:

在2022年10月之前,对主要科学数据库 (PubMed,科学网,Cochrane,Scopus) 进行全面搜索.
根据预定义的资格标准,包括相关的随机对照试验 (RCT).
计算和报告加权平均差异 (WMDs) 的统计显著性设置为p < 0.05.

主要成果:

洋补充剂显著改善了身体脂肪百分比,LDL-c,总胆固醇,HDL-c,静脉血压,阿迪波涅丁和AST.
干预>12周和剂量>300毫克/天显示体重,腰围,BMI,身体脂肪,脂质概况和血压显著改善.
观察到AST和ALT的显著改善,用更高的剂量.

结论:

洋补充剂显示了改善代谢健康参数的潜力.
较长的干预期和较高的洋剂量都增加了心脏代谢效益.
洋代表了一种有希望的功能性食品,用于管理代谢健康指标.

关键词:

进行元分析分析.代谢参数代谢参数洋补充剂的使用方法有机试验试验 (RCT) 是指一个试验试验.

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