基于扭曲的分子内电荷转移探针的三酸阻燃剂的高灵敏性和选择性离线光平台
Yulu Tian1, Xiaoying Huang1, Hangzhou Li1
1Faculty of Geosciences and Environmental Engineering, Southwest Jiaotong University, Chengdu 611756, China.
Analytica chimica acta
|December 6, 2023
概括
一个新的"打开"光传感器检测到三酸 (TCP),一种新兴的污染物. 这种方法为分析TCP的传统技术提供了快速,灵敏和选择性的替代方案.
科学领域:
- 环境化学环境化学
- 分析化学 分析化学
- 传感器技术 传感器技术
背景情况:
- 三酸 (TCP) 是一种新兴的有机阻燃剂 (OPFR) 污染物,具有显著的神经毒性和生殖毒性问题.
- 传统的方法,如GC-MS和LC-MS/MS用于TCP检测是敏感的,但昂贵的,耗时的,需要大型设备.
- 对于TCP检测而言,急需快速,高效和用户友好的分析方法.
研究的目的:
- 开发一种新的,高效的光传感策略,用于检测三酸 (TCP).
- 建立一个具有成本效益和快速的分析方法来监测新出现的OPFR污染物.
主要方法:
- 开发一种"打开"光传感策略,使用分子转子探头,9-(2,2-dicyanovinyl) -julolidine (DCVJ).
- 研究涉及曲分子内电荷转移 (TICT) 的传感机制,该传感机制由疏水相互作用和结合效应调节.
- 使用动态光散射和光寿命分析来描述传感性能.
主要成果:
- 在DCVJ探测器与TCP相互作用时显著增强光强度,表明"打开"响应.
- 传感平台展示了快速响应时间,高选择性,广泛的线性范围 (201200 ng mL-1,16008000 ng mL-1),以及低的检测极限 (4.82 ng mL-1).
- 该机制涉及DCVJ受约束的分子旋转,由于疏水相互作用和与TCP的结合,调节TICT过程.
结论:
- 开发的光传感平台为TCP检测提供了一种简单,高效,敏感和选择性的方法.
- 这种方法超过了以前报告的基于光的OPFR检测方法的性能.
- 这项工作为有效监测新出现的OPFR污染物提供了一个有希望的新途径.
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