儿童年龄的脑静脉血栓:危险因素和预后
Inês Pais-Cunha1, Ana I Almeida2, Ana R Curval1
1Serviço de Pediatria, Unidade Autónoma Gestão da Mulher e da Criança, Centro Hospitalar Universitário de São João, Porto, Portugal.
Neuropediatrics
|December 6, 2023
概括
儿童脑静脉血栓形成 (CVT) 的危险因素,如永久性疾病和鼻干扰,预测严重的结果. 这些因素的早期发现和管理对于减少儿科CVT发病率和死亡率至关重要.
科学领域:
- 儿科神经学 儿科神经学
- 血管神经学 血管神经学
- 儿科重症监护中心儿童重症监护中心
背景情况:
- 大脑静脉血栓塞 (CVT) 是儿童罕见但严重的疾病.
- 与成年人相比,关于儿科CVT的风险因素和长期结果的研究有限.
研究的目的:
- 确定与儿科CVT临床表现相关的风险因素.
- 为了确定与CVT儿童的长期后果相关的因素.
主要方法:
- 对被诊断患有CVT的儿科患者的回顾性分析.
- 从2008年至2020年期间从一家三级医院收集的数据.
- 包括54名儿科住院患者.
主要成果:
- 确定了永久的危险因素 (例如恶性瘤) 和短暂的危险因素 (例如感染).
- 发现多重静脉鼻干扰 (65%) 和深静脉系统干扰.
- 观察到内出血 (17%) 和脑梗塞 (9%).
- 与严重表现相关的永久性风险因素 (p=0.043).
- 脑梗塞和出血与严重的后果相关 (p=0.006和p=0.03).
结论:
- 永久性危险因素,多重鼻干扰,内出血和脑梗塞预测儿科CVT的预后会更差.
- 早期识别和管理风险因素对于减轻CVT严重性和改善结果至关重要.
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