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Updated: Jul 9, 2025

Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line
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Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line

Published on: August 2, 2021

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缺少RCN1抑制了口腔状细胞癌的进展和THP-1巨细胞M2极化

Han Liu1,2, Haiyang Guo3, Yuehan Wu1,2

  • 1Department of Stomatology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Scientific reports
|December 6, 2023
PubMed
概括

视网素1 (RCN1) 的上调与口腔状细胞癌 (OSCC) 的预后不佳相关. 抑制RCN1会减少OSCC细胞的生长,迁移,入侵和M2巨细胞的两极分化,这表明RCN1是OSCC的潜在治疗标.

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