用于预测患有脑膜瘤的患者心血管疾病死亡率的诺姆图:一种竞争性风险分析
Ruoran Wang1, Jing Zhang1, Min He2
1Department of Neurosurgery, West China Hospital, Sichuan University, No. 37, Guo Xue Xiang, Chengdu, 610041, Sichuan Province, China.
Neurosurgical review
|December 6, 2023
概括
与普通人群相比,脑膜瘤患者面临的心血管死亡风险明显更高. 这项研究确定了关键的风险因素,并开发了这些患者心血管死亡的预测工具.
科学领域:
- 在瘤学瘤学.
- 心血管医学 心血管医学
- 流行病学 流行病学
背景情况:
- 脑膜瘤患者表现出心血管死亡的风险较高.
- 了解这些风险对于患者管理至关重要.
研究的目的:
- 调查脑膜瘤患者心血管死亡的发病率和风险因素.
- 开发心血管特异性生存的预测模型.
主要方法:
- 从监测流行病学和最终结果 (SEER) 数据库 (2004-2016) 分析了94 067名脑膜瘤患者.
- 为心血管疾病计算标准化死亡率 (SMR).
- 细灰竞争风险回归和名ogram构造的应用.
主要成果:
- 与一般人群相比,脑膜瘤患者与心血管疾病相关的SMR为25.31.
- 确定的风险因素包括年龄,男性性别,种族,婚姻状况,保险,瘤特征和手术选择.
- 诺米图表显示出良好的预测准确性 (C指数0.730在培训中,0.726在验证中).
结论:
- 脑膜瘤患者的心血管死亡风险大大增加.
- 一个经过验证的诺姆图可以有效预测心血管死亡率,有助于临床风险因素管理.
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