肥胖与剖腹产后住院患者阿片类药物消费的关联
Abigail L Strong1, Alina Tvina2, Rachel K Harrison1,3
1Department of Obstetrics and Gynecology at Medical College of Wisconsin, Milwaukee, WI, USA.
International journal of obesity (2005)
|December 6, 2023
概括
在剖腹产产后,孕产妇的肥胖症并没有增加每小时的阿片类药物需求. 然而,肥胖和严重肥胖的女性更有可能在剖腹产后消耗更多的阿片类药物.
科学领域:
- 产科和妇科 产科和妇科
- 麻醉学 麻醉学
- 公共卫生 公共卫生
背景情况:
- 肥胖和处方阿片类药物滥用是美国重要的公共卫生问题.
- 在接受剖腹产并接受产后阿片类止痛药的肥胖妇女中观察到一个常见的重叠.
研究的目的:
- 调查产妇肥胖和剖腹产后住院患者的阿片类药物消费之间的关系.
主要方法:
- 对2015-2018年剖腹产产生的回顾性队列研究.
- 从分娩后24小时开始,以每小时的吗啡毫等值 (MME/h) 计量的阿片类药物消费.
- 在非肥胖 (BMI 18.5-29.9 kg/m2),肥胖 (BMI 30.0-39.9 kg/m2) 和病态肥胖 (BMI ≥ 40.0 kg/m2) 组中,MME/h的比较.
主要成果:
- 肥胖和严重肥胖的群体在单变量分析中显示出更高的MME/h (p < 0.001).
- 多变量分析显示,每小时的MME消费没有显著差异.
- 肥胖 (aOR 1.42) 和致病性肥胖 (aOR 1.60) 患者更有可能处于MME/h消费的最高四分位数 (分别p < 0.016和p < 0.005).
结论:
- 孕产妇肥胖与剖腹产后每小时的阿片类药物消费增加无关.
- 然而,肥胖和致病性肥胖患者显示,他们更有可能处于阿片类药物消费的前四分之一.
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