伴随性喘与暴露于空气污染物的儿童鼻炎的严重程度有关
Sai-Wai Ho1,2, Ko-Huang Lue3, Shan-Ming Chen2
1Department of Emergency Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan, ROC.
Pediatric research
|December 6, 2023
概括
喘在暴露于空气污染的年轻男性中加剧过敏性鼻炎 (AR) 的严重程度,增加不适和鼻子问题. 喘,鼻炎和污染物之间的这种联系是研究中的男性特有的.
科学领域:
- 环境健康 环境健康
- 儿科过敏 儿科过敏
- 呼吸系统医学 呼吸系统医学
背景情况:
- 空气污染对患有喘的儿童过敏性鼻炎 (AR) 严重性的影响尚不清楚.
- 之前的研究并没有专门研究喘和空气污染物对儿科患者鼻炎症状的联合影响.
研究的目的:
- 研究伴随性喘对暴露于各种空气污染物的儿童过敏性鼻炎的严重程度的影响.
- 为了确定喘是否改变了空气污染物暴露和儿童鼻炎结果之间的关系.
主要方法:
- 从台湾的一家医院招募了6至13岁的患有过敏性鼻炎 (AR),喘或没有喘的儿童.
- 分析了生活质量得分,鼻峰呼吸流量,临床访问频率和PM10,PM2.5,NO2和NMHC度之间的相关性.
- 一个AR患者的数据库被用来比较临床访问时间与空气污染物水平.
主要成果:
- 在AR和喘的男性儿童中,较高的PM10,PM2.5,NO2和NMHC水平与增加的鼻炎不适 (生活质量得分) 和更频繁的临床访问相关.
- 鼻子炎症和阻塞,以鼻子下部的峰值呼气流量为标志,也与这些男孩的空气污染物度更高有关.
- 这些相关性在男性儿童中特别观察到,而不是女性儿童.
结论:
- 伴随性喘显著增加了男性儿童的鼻炎的严重程度与AR当暴露于空气污染物.
- 由于暴露于空气污染物而增加的鼻腔阻塞和炎症可能是男性观察到的这种关联的潜在机制.
- 这些发现强调了儿童过敏性鼻炎患者的性别特异性脆弱性,这些患者患有喘,暴露于环境污染物.
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