从微生物到分子:对微生物驱动的抗氧化生成的审查
Soyoung Jeong1,2,3, Jong-Hyun Jung1, Kwang-Woo Jung1
1Radiation Biotechnology Division, Korea Atomic Energy Research Institute, Jeongeup, 56212, Republic of Korea.
World journal of microbiology & biotechnology
|December 6, 2023
概括
抗氧化可以对抗由氧化应激引起的细胞损伤. 本综述强调了用于生产这些有益的微生物及其酶,指导了未来的发现.
科学领域:
- 生物化学 生物化学
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
背景情况:
- 活性氧物种 (ROS) 的氧化应激会损害细胞,导致健康障碍.
- 抗氧化 (2-20种氨基酸) 抵消ROS,并用于食品,营养药品和药品中.
- 现有的研究涵盖了抗氧化的起源,生产,结构-活性和机制,但忽视了微生物的作用.
研究的目的:
- 通过酶解水解和发酵全面审查微生物及其蛋白酶在生产抗氧化中的作用.
- 为了探索由微生物产生的内源性.
- 引导新型抗氧化生成生物的发现.
主要方法:
- 文献综述侧重于微生物参与抗氧化生产.
- 在酶化水解中分析来自细菌,真菌和酵母的蛋白酶.
- 检查微生物发酵过程用于生成.
主要成果:
- 微生物,包括细菌,真菌和酵母,对于通过酶解水解和发酵产生抗氧化来说至关重要.
- 特定的微生物蛋白质在从前体蛋白释放抗氧化中发挥关键作用.
- 微生物还可以产生内源性抗氧化.
结论:
- 微生物酶和发酵对于抗氧化的生产至关重要.
- 了解微生物的作用可以导致发现产生这些的新生物.
- 本综述为探索微生物对抗氧化生成的贡献提供了基础.
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