尿路与女性乳腺癌之间的关联:基于人口的跨部门研究
Daojun Hu1, Li Zhang1, Bing Qin1
1Department of Clinical Laboratory, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, 202150 Shanghai, China.
Discovery medicine
|December 7, 2023
概括
尿中的含量与女性乳腺癌 (FBC) 的风险增加有关. 这项研究发现了正相关性,表明暴露可能导致FBC发展.
科学领域:
- 环境健康 环境健康
- 在瘤学瘤学.
- 毒理学 毒理学 毒理学
背景情况:
- 以前的研究将血清含量与女性乳腺癌 (FBC) 风险联系起来.
- 尿中的含量与FBC之间的关联仍然不清楚.
研究的目的:
- 在美国人口中调查尿含量与FBC风险之间的潜在关联.
主要方法:
- 一项横截面病例控制研究利用了来自国家健康和营养检查调查 (NHANES) (1999-2018) 的数据.
- 分析了2795名女性参与者 (210名FBC病例,2585名对照).
- 尿中的含量使用诱导合等离子体质谱法测量,并通过多变量逻辑回归分析.
主要成果:
- 尿中的与FBC风险有正相关性 (OR,2.16;95% CI: [1.18,3.95],p < 0.05).
- 尿的较高四分位数 (Q3和Q4) 与最低四分位数 (Q1) 相比,与增加的FBC几率有关.
- 在各种子组中,在尿和FBC之间没有发现显著的相互作用效应.
结论:
- 在美国,尿中的含量可能与女性乳腺癌有关.
- 研究结果表明,环境暴露可能是导致FBC的因素.
相关概念视频
Statistical Methods for Analyzing Epidemiological Data
372
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
372
Cancer Prevention
6.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.2K
Cancer Survival Analysis
356
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
356


