麻疹和天花感染:尼日利亚南部的一系列病例
Juliet I Mmerem1, Chukwudi C Umenzekwe2, Simon M Johnson3
1Department of Medicine, University of Nigeria Teaching Hospital, Ituku/Ozalla, Enugu, Enugu State, Nigeria.
The Journal of infectious diseases
|December 7, 2023
概括
在尼日利亚确认的mpox病例中,超过四分之一发生了mpox和水联合感染. 这种高频率突显了非洲需要快速获得疹和水疫苗的需要.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 马波克斯 (原名水) 和水联合感染对公众健康构成重大挑战.
- 了解这种共感染的临床流行病学特征对于有效的管理和预防策略至关重要.
研究的目的:
- 描述尼日利亚mopox-chickenpox共感染的临床流行病学特征.
- 评估与mopox单一感染相比,共感染患者的并发症率.
主要方法:
- 尼日利亚确诊的mopox病例的回顾性队列分析 (2022年1月 - 2023年3月).
- 通过实时聚合酶链反应 (RT-PCR) 确认mopox和水.
主要成果:
- 在56例确诊的mopox病例中,有16例 (28.6%) 同时感染了水.
- 同感染的患者出现的并发症 (56.3%) 比单独服用mopox的患者要多得多 (22.5%,P = .015).
- 麻疹病例的中位数年龄为29岁,其中60.7%为男性.
结论:
- 莫波克斯和水联合感染的大量频率突显出迫切需要加强疫苗的可获得性.
- 建议在非洲地区加快部署mopox和天花疫苗,以减轻共感染风险.
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