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Updated: Jul 9, 2025

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Published on: February 21, 2018

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PELI2通过IL-7R表达来调节早期B细胞原始体分化和相关的白血病

Yan Xu1, Qian Zhou1, Xiaoming Wang2

  • 1Key Lab of Chemical Biology (MOE), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China; NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250012, China; Department of Pharmacology, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012.

Haematologica
|December 7, 2023
PubMed
概括

佩利诺2 (PELI2) 通过稳定PU.1和TCF3,调节IL-7R表达,对B细胞发育至关重要. 这一发现为B细胞前体急性淋巴细胞白血病 (BCP-ALL) 提供了潜在的治疗策略.

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