服用似乎对患有低血症的急性胰腺炎患者没有益处
Tianao Yan1,2,3, Yifei Ma1,2,3, Zheng Wang1,2,3
1Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Journal of hepato-biliary-pancreatic sciences
|December 7, 2023
概括
疗法不会改善急性胰腺炎患者的生存率. 这种治疗与更长的住院和重症监护室住院有关,但不影响死亡率.
科学领域:
- 临界护理医学 临界护理医学
- 胃肠病学 胃肠病学
- 内部医学 内部医学
背景情况:
- 低血是急性胰腺炎 (AP) 患者进入重症监护室 (ICU) 的常见并发症.
- 在AP患者的低血症中,的治疗益处尚不清楚.
- 这项研究调查了疗法对AP患者治疗结果的影响.
研究的目的:
- 为了确定疗法是否改善急性胰腺炎患者的预后,这些患者经历了低血症.
- 为了评估的管理和死亡率 (住院,28天,ICU) 和停留时间 (LOS) 在AP患者与低血症之间的关联.
主要方法:
- 来自MIMIC-IV数据库的807名急性胰腺炎患者的逆向分析.
- 使用倾向得分匹配 (PSM) 和反向概率加权 (IPTW) 来控制基线差异.
- 使用多变量回归分析来评估治疗对患者结果的影响.
主要成果:
- 620名患者 (76.8%) 接受了治疗;187人没有.
- 疗法与住院,28天或ICU死亡率没有显著关联.
- 的使用与长时间的医院LOS (效果估计:6.18) 和ICU LOS (效果估计:1.72) 有关.
结论:
- 的使用对患有低血症的急性胰腺炎患者在死亡率方面没有好处.
- 疗法与显著更长的住院和ICU停留时间有关.
- 在接受专用肠道输液,早期疗法或不同程度的低血症的小组中没有观察到任何益处.
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