沙特阿拉伯发育迟缓儿童皮层复杂性减少
Abdullah H Abujamea1, Mohammed Almosa2, Mohammad Uzair3
1Department of Radiology and Medical Imaging, King Saud University Medical City, King Saud University, Riyadh, SAU.
Cureus
|December 7, 2023
概括
这项研究发现沙特阿拉伯儿童发育迟缓 (DD) 的结构性大脑异常. 神经成像显示了关键大脑区域的形,表明神经发育受损,以及早期诊断的潜在生物标志物.
科学领域:
- 神经成像是一种神经成像.
- 发育神经科学的发展神经科学.
- 儿科神经学 儿科神经学
背景情况:
- 发育迟缓 (DD) 是一种影响多个领域的神经发育障碍.
- 先进的神经成像技术可以识别DD中的结构性大脑异常.
- 在沙特阿拉伯人口中对DD神经解剖学的研究有限.
研究的目的:
- 调查沙特阿拉伯儿童DD的皮质和皮质下区域的神经解剖学异常.
- 确定潜在的神经解剖学生物标志物,用于早期诊断和理解DD.
主要方法:
- 使用T1加权MRI (1毫米厚度) 进行结构性脑部成像.
- 对29名DD儿童和年龄相匹配的健康对照进行分析.
- 灰质 (GM) 和白质 (WM) 结构的比较.
主要成果:
- 在沙特儿童DD中发现了GM和WM结构的显著差异.
- 在尾状核,白色球体,额头,以及其他特定区域观察到的形.
- 结果表明神经发育受损,导致DD相关的障碍.
结论:
- 这项研究强调了沙特儿童DD的神经解剖学差异.
- 在DD中显而易见的皮层和皮下皮层异常.
- 结构分析可能有助于早期诊断DD,并了解其对认知和情绪功能的影响.
相关概念视频
Information Processing Approach
42
The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...
42
Autism Spectrum Disorder
100
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
100
Learning Disabilities
149
Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...
Dyslexia
Dyslexia is a...
149
Attention-Deficit/Hyperactivity Disorder
68
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
68


