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面具揭开面具:访问一个罕见的瘤,强调细胞形态特征

Michael L Anthony¹, Neha Kumari², Reshma Jeladharan³

¹Department of Pathology, Andhra Medical College, Vishakhapatnam, Andhra Pradesh, India.

Journal of cytology

|December 7, 2023

概括

分泌性癌症 (SC) 诊断现在可以通过细胞学实现,使用特征性细胞形态学特征和免疫组织化学 (IHC). 在大多数情况下,这避免了对光 in situ 杂交 (FISH) 的需求.

科学领域:

病理学病理学病理学
细胞病理学细胞病理学
在瘤学瘤学.

背景情况:

分泌性癌 (SC) 是最近发现的一种瘤类型.
以前在细胞学上被误诊为乙细胞癌.
最初的诊断依赖于通过FISH通过ETV6:NTRK3基因融合检测.

研究的目的:

为了确定用于诊断SC的细胞形态特征,使用细针吸入细胞学.
评估免疫组织化学 (IHC) 在SC诊断中的实用性.
根据细胞学发现,区分SC与其他实体.

主要方法:

六个经组织学确认的SC病例的回顾性审查.
精细针吸收 (FNA) 细胞学涂抹的分析.
检查细胞块,如果有.

主要成果:

在FNA涂抹中,SC病例呈现出细胞质真空化,乳头形成和平淡的核特征.
在确认诊断方面,S-100和mammaglobin IHC是非常有效的.
患者主要是男性,平均年龄为35.2岁.

结论:

细胞形态特征可以帮助从细胞学直接诊断SC.
像S-100和乳母球蛋白这样的IHC标志物对于确定诊断至关重要.
识别这些特征有助于排除其他差异诊断.

关键词:

组织学细胞学相关性在IHC中,IHC是指IHC.腺腺体腺体唾液腺细胞学唾液腺细胞学这种癌症是分泌性癌瘤.

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