在全关节整形术后深静脉血栓形成预防的趋势:2016年至2021年
Mallory C Moore1, Jeremy A Dubin1, Sandeep S Bains1
1LifeBridge Health, Sinai Hospital of Baltimore, Rubin Institute for Advanced Orthopedics, Baltimore, MD, USA.
Journal of orthopaedics
|December 7, 2023
概括
关节整形术 (THA) 后,阿司匹林越来越多地用于静脉血栓塞栓症 (VTE) 预防,显示了较低的静脉血栓塞栓症和输血率. 这表明阿司匹林在适当选择的接受THA的患者中是有效的.
科学领域:
- 整形外科手术 整形外科手术
- 心血管医学 心血管医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 静脉血栓塞栓症 (VTE) 是关节整形术 (THA) 后的一个重大并发症.
- 有效的VTE预防对于降低与THA相关的患者发病率,死亡率和医疗费用至关重要.
研究的目的:
- 评估从2016年到2021年使用VTE预防的趋势.
- 为了确定手术后静脉瘤和THA后输血的发生率.
- 为了确定与不同预防药物相关的90天VTE和输血的危险因素.
主要方法:
- 从2016年1月1日到2022年12月31日,对全国所有付款人的数据库进行分析.
- 在THA患者中评估阿司匹林,达比加特兰,埃诺沙巴林,里瓦罗克萨班和华法林的利用趋势.
- 对90天术后静脉动脉瘤和输血率的评估.
主要成果:
- 从2016年至2021年,阿司匹林是最常用的静脉瘤预防药物 (n=36,346).
- 90天VTE的独立风险因素包括CKD,COPD,CHF,肥胖,以及使用达比加特兰,埃诺沙巴林,里瓦罗克萨班或华法林 (p <0.05).
- 与其他药物相比,阿司匹林使用量的增加与静脉动脉突发症和输血后THA的发病率较低相关.
结论:
- 与其他药物相比,阿司匹林在THA输血后的VTE和输血率较低.
- 在适当选择的THA患者中,阿司匹林用于静脉瘤预防的使用越来越多,似乎是安全有效的.
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