在患有多发性硬化症的患者中,对椎脊髓横截面区域的MRI评估
Haider N Al-Tameemi1, Hayder K Hassoun1, Israa Q Mohammed2
1Middle Euphrates Neurosciences Center, Faculty of Medicine, Kufa University, Al-Najaf, Iraq.
Journal of neurosciences in rural practice
|December 7, 2023
概括
与健康个体相比,多发性硬化症 (MS) 患者的椎脊髓截面面积 (CSA) 减少. 这种缩与疾病持续时间和残疾相关,特别是在渐进的MS中.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 神经免疫学 神经免疫学
背景情况:
- 在多发性硬化症 (MS) 中经常观察到脊髓异常,包括缩宫髓.
- 通过MRI评估椎脊髓截面面积 (CSA),可以了解MS相关的神经退行.
研究的目的:
- 在多发性硬化症 (MS) 患者中使用磁共振成像 (MRI) 评估宫脊髓截面面积 (CSA).
- 为了在MS患者和健康对照者之间比较宫CSA.
主要方法:
- 60名参与者 (30名多发性硬化患者,30名对照组) 接受了宫MRI.
- 脊髓CSA是在从C2到C7脊椎水平的轴向T2加权图像上测量的.
主要成果:
- 与对照人群相比,多发性硬化患者的宫CSA平均值在C2,C7显著下降,平均C2-7为C2.
- 在宫CSA和MS疾病持续时间和残疾分数之间发现了强烈的反相关性.
- 宫CSA减少在患有二次进展性MS的患者中更加明显.
结论:
- 与健康个体相比,MS患者的宫脊髓CSA显著减少.
- 渐进性MS类型和更长的疾病持续时间/更高的残疾分数与更大的宫缩缩有关.
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