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Updated: Jul 9, 2025

A Lectin HPLC Method to Enrich Selectively-glycosylated Peptides from Complex Biological Samples
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Published on: October 1, 2009

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选择性和口服可用的galectin-1抑制剂的发现

Fredrik R Zetterberg1, Carl Diehl2, Maria Håkansson2

  • 1Galecto Biotech AB, Sahlgrenska Science Park, Medicinaregatan 8 A, SE-413 46 Gothenburg, Sweden.

Journal of medicinal chemistry
|December 7, 2023
PubMed
概括

研究人员发现了新的口服可用的化合物,这些化合物向了加勒-1. 这些强大的加列-1抑制剂,如GB1490,在小鼠中显示出高亲和力,特异性和优异的口服生物利用性.

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